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BCR-ABL Testing, BCR-ABL Test, BCR-ABL International Scale

BCR-ABL Testing: Resources to help molecular pathologists standardize on the international scale for BCR-ABL quantitative measurements and BCR-ABL Testing

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BCR-ABL Testing, BCR-ABL Test, BCR-ABL International Scale | whereareyouontheis.com Reviews
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BCR-ABL Testing: Resources to help molecular pathologists standardize on the international scale for BCR-ABL quantitative measurements and BCR-ABL Testing
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BCR-ABL Testing, BCR-ABL Test, BCR-ABL International Scale | whereareyouontheis.com Reviews

https://whereareyouontheis.com

BCR-ABL Testing: Resources to help molecular pathologists standardize on the international scale for BCR-ABL quantitative measurements and BCR-ABL Testing

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whereareyouontheis.com whereareyouontheis.com
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BCR-ABL Testing, BCR-ABL Testing and the International Scale, BCR-ABL Test

http://www.whereareyouontheis.com//BCR-ABLTesting.aspx

The IS is anchored to the baseline BCR-ABL1 expression level from the International Randomized Study of Interferon vs. STI571 (IRIS) trial (100% IS) with a major molecular response (MMR) corresponding to 0.1% IS. (Hughes et al., N Engl J Med 2003). The IRIS and follow up studies have demonstrated that achieving MMR, or a 3-log reduction in BCR-ABL1 expression from the standardized baseline level, is a key clinical outcome. This website is sponsored by Asuragen ASURAGEN HOME.

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BCR-ABL Testing, BCR-ABL Test, BCR-ABL International Scale

http://www.whereareyouontheis.com//Default.aspx

INTERNATIONAL SCALE COMMON QUESTIONS. What is a BCR-ABL1 monitoring test? How are BCR-ABL1 monitoring results reported? What is the International Scale for standardization of quantitative BCR-ABL1 result reporting? What is the importance of the IS? How do I standardize my lab to the IS? Can any lab become standardized to the IS? Once my lab has become standardized to the IS, how do I maintain a valid IS conversion factor? Is there an IS reference material available? Can e1a2 be reported on the IS? The In...

3

BCR-ABL Testing and International Scale Webinars, BCR-ABL Tests

http://www.whereareyouontheis.com//BCR-ABLWebinar.aspx

Monitoring CML Patients by RT PCR on the International Scale. Presented by Nick Cross, MA, PhD, FRCPath Professor of Human Genetics at Wessex Regional Genetics Laboratory, U.K. Click here to view this webinar recorded September 26th, 2011. If you are having trouble viewing this video install the gotomeeting video codec found here. Click here to view Dr. Cross's PowerPoint slides. Comprehensive coverage of why, when and how IS standardisation was established. Review the definitions of response. BCR-ABL1 Q...

4

BCR-ABL Test, BCR-ABL Testing, BCR-ABL International Scale

http://www.whereareyouontheis.com/BCR-ABLPublications.aspx

Gabert J, Beillard E, van der Velden VH, Bi W, Grimwade D, Pallisgaard N et al. Standardization and quality control studies of 'real-time' quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia - a Europe Against Cancer program. Leukemia 2003; 17:2318-2357. N Engl J Med 2003; 349: 1423-1432. Clin Cancer Res 2005; 11: 3425-3432. Blood 2006; 108: 28-37. Baccarani M, Saglio G, Goldman J, Hochhaus A, Simonsson B, Appelbaum F et al&#4...

5

BCR-ABL Test, BCR-ABL Testing, BCR-ABL International Scale

http://www.whereareyouontheis.com//BCR-ABLPublications.aspx

Gabert J, Beillard E, van der Velden VH, Bi W, Grimwade D, Pallisgaard N et al. Standardization and quality control studies of 'real-time' quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia - a Europe Against Cancer program. Leukemia 2003; 17:2318-2357. N Engl J Med 2003; 349: 1423-1432. Clin Cancer Res 2005; 11: 3425-3432. Blood 2006; 108: 28-37. Baccarani M, Saglio G, Goldman J, Hochhaus A, Simonsson B, Appelbaum F et al&#4...

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pattimoonis.blogspot.com pattimoonis.blogspot.com

patti moonis: December 2014

http://pattimoonis.blogspot.com/2014_12_01_archive.html

Slaying giants. Raising awareness. Spreading blessings. Patti fights CML with the help of many. Walk with us. Laugh with us. Cry with us. The Caregiver takes a sick day. A dear friend sent me this quote yesterday. The Caregiver is home sick today. And he's not a good sick person. He's moaning the same if he has a sore throat or if he has the flu. You'd think, from his behavior, that he's been diagnosed with Ebola. Makes no sense to me.). Then, if Little H hasn't already woken up, I get her up. This morni...

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INTERNATIONAL SCALE COMMON QUESTIONS. What is a BCR-ABL1 monitoring test? How are BCR-ABL1 monitoring results reported? What is the International Scale for standardization of quantitative BCR-ABL1 result reporting? What is the importance of the IS? How do I standardize my lab to the IS? Can any lab become standardized to the IS? Once my lab has become standardized to the IS, how do I maintain a valid IS conversion factor? Is there an IS reference material available? Can e1a2 be reported on the IS? The In...

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