Insulin-Degrading Enzyme known for long, remains poorly understood. It is involved in the clearance of physiologically important peptides and found in both intracellular and extracellular compartments. IDE was named on the basis of its affinity for, and ability to degrade insulin. IDE is thus suspected to be involved in the physiopathology of diabetes. Indeed it mediates the degradation of insulin ...
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Our objective | insulysin.org Reviews
https://insulysin.org
Insulin-Degrading Enzyme known for long, remains poorly understood. It is involved in the clearance of physiologically important peptides and found in both intracellular and extracellular compartments. IDE was named on the basis of its affinity for, and ability to degrade insulin. IDE is thus suspected to be involved in the physiopathology of diabetes. Indeed it mediates the degradation of insulin ...
insulysin.org
Insulysin
http://www.insulysin.org/plan.php?langue=english&cle_menus=1143742438
This page has been moved or deleted. Back to the site. Http:/ www.insulysin.org. 2016 Design : Antalys.
This section gathers key publications on IDE
http://www.insulysin.org/list_infos/this%20section%20gathers%20key%20publications%20on%20ide/1011306087/list1366641555.html
See our new publication in Nature Comm that shows for the first time the effect of a catalytic site inhibitor of IDE in vivo:. Deprez-Poulain, R., et al Nature Comm., 2015. This section gathers key publications on IDE. First catalytic site inhibitor of IDE in vivo. Dual binders of IDE full SAR. Eur J Med Chem. 90: 547-567 doi:10.1016/j.ejmech.2014.12.005. Dual binders of IDE inhibit amyloid beta catabolism in vitro and in cells. European Journal of Medicinal Chemistry. IDE and the PI3K pathway* *. Leal, ...
Insulysin
http://www.insulysin.org/form.php?langue=english&cle_menus=1023174344
This page has been moved or deleted. Back to the site. Http:/ www.insulysin.org. 2016 Design : Antalys.
PDB Structures
http://www.insulysin.org/web/gallery/1011306087/list1187970068/f1.html
See our new publication in Nature Comm that shows for the first time the effect of a catalytic site inhibitor of IDE in vivo:. Deprez-Poulain, R., et al Nature Comm., 2015. Follow the links below to download our PDB structures of IDE complexed with our modulators:. 2016 Design : Antalys.
Our objective
http://www.insulysin.org/web/our%20objective/1011306087/list1023110705/f1.html
See our new publication in Nature Comm that shows for the first time the effect of a catalytic site inhibitor of IDE in vivo:. Deprez-Poulain, R., et al Nature Comm., 2015. Our objective is to produce well designed chemical probes to explore the role of this enzyme to untangle its role, taking into account the peculiar structure of this protein. 2016 Design : Antalys.
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Insulin Degrading Enzyme modulators
http://www.deprezlab.fr/web/insulin%20degrading%20enzyme%20modulators/1011306087/list1187970172/f1.html
Insulin Degrading Enzyme modulators. Contracts, industrial partners. Insulin Degrading Enzyme modulators. Insulin Degrading Enzyme modulators. Pr Rebecca Deprez-Poulain PhD PharmD MRSC. Damien Bosc - Ass. Prof. Paul Hermant - PhD student. Jouda Jakhlal - PostDoc. Julie Dumont - Ass Eng. Florence Leroux PhD -PharmD. Gonzague Berte - PhD student. Damien Bosc PhD - Post-doc. Tristan Verdelet PhD -Post-doc. Jamal Elbakali PhD -Post-doc. Cyril Ronco PhD - Post-Doc. Xavier Marechal PhD - Post-doc.
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Le Clos des Récollets. ECHA Board of Appeal Forum. European Silica Fume Committee. Société Belge de Parodontologie. Aide et Soins à Domicile. Société de Chimie Thérapeutique. Le Jardin Des Fées. Société Belge de Parodontologie. Nos réalisations : Sites internet - intranet - extranet. LE CLOS DES RECOLLETS. EU SILICA FUME COMMITTEE. Rue de l'Escalette 31b3. 7500 Tournai - Belgique. Tel : 32 69 847363. TVA : BE 0473464423.
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Our objective
See our new publication in Nature Comm that shows for the first time the effect of a catalytic site inhibitor of IDE in vivo:. Deprez-Poulain, R., et al Nature Comm., 2015. Our objective is to produce well designed chemical probes to explore the role of this enzyme to untangle its role, taking into account the peculiar structure of this protein. 2018 Design : Antalys.
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