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Home - Orphan Enzyme Project

The Orphan Enzymes Project (OEP) is dedicated to connecting modern genome sequencing methods with a century of

http://www.orphanenzymes.org/

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Home - Orphan Enzyme Project | orphanenzymes.org Reviews

https://orphanenzymes.org

The Orphan Enzymes Project (OEP) is dedicated to connecting modern genome sequencing methods with a century of

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1

Please take a quick survey about sequence deposition and EC numbers - Orphan Enzyme Project

http://www.orphanenzymes.org/2014/04/16/please-take-quick-survey-sequence-deposition-ec-numbers

What’s an orphan? Please take a quick survey about sequence deposition and EC numbers. In a perfect world, each sequence that is deposited into a resource such as GenBank would have a correct EC number assigned to it. We would love to have your input on some solutions that would make it easier to make sure GenBank and similar entries also get appropriate EC numbers assigned. Please click here to provide your input. Posted in community input. The orphans we find have a big impact. OEP is getting populated.

2

Database - Orphan Enzyme Project

http://www.orphanenzymes.org/database

What’s an orphan? The date files available for download below present orphan enzymes and supporting data collected as part of the work described in our paper Finding sequences for over 270 Orphan Enzymes. Think you have a new orphan enzyme or other information to add to our database? Please let us know by using our contact form. Read our Frequently Asked Questions. Page for guidelines about submitting new orphan enzymes and other updates. Orphan enzyme supporting data. Download the data files.

3

News - Orphan Enzyme Project

http://www.orphanenzymes.org/updates

What’s an orphan? New paper – Finding Sequences for over 270 Orphan Enzymes. We’re pleased to announce the publication of our new paper Finding Sequences for over 270 Orphan Enzymes. In this paper, we describe how we used a combined literature, patent, and database evaluation method to find sequences for 275 orphan enzymes. During this research, we learned quite a bit about how orphan enzymes happen. We think we’ve developed some pretty good ways of preventing future orphan enzymes, too. So what’s ...

4

People - Orphan Enzyme Project

http://www.orphanenzymes.org/people

What’s an orphan? The Current OEP Team:. Alexander G. Shearer (PI). Former OEP Team Members:. From the research community:. Kristian B. Axelsen. Alexander G. Shearer (PI). Alex comes to the project from Clover Collective. Find Alex’s papers via PubMed. Alex’s personal website. Describing the combined literature, patent, and database search that netted us over 270 orphan sequences. Tomer is currently a grad student in the Biomedical Informatics. Find Tomer’s papers via PubMed. Christine’s work includes de...

5

What's an orphan? - Orphan Enzyme Project

http://www.orphanenzymes.org/whats-an-orphan-enzyme

What’s an orphan? What’s an orphan? Is an enzyme activity that has been experimentally characterized but for which we lack amino-acid or nucleotide sequence data. When we say that an enzyme activity has been experimentally characterized we mean that at a minimum its reactants and products are known. In most cases, researchers have also identified a wealth of other data such as molecular weights, isoelectric points, reaction kinetics, and more. Been sequenced (the other 75%). Why do orphan enzymes matter?

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Home - Orphan Enzyme Project

What’s an orphan? Finding sequences for orphan enzymes. To access our database of orphan enzymes and supporting information. Interested in learning about finding sequences for orphan enzymes or learning how to prevent them in the first place? Try one of our tutorials. Please consider taking a few minutes to provide your input. About sequence deposition and EC numbers. Resolving a key problem in modern biology. In addition, every time we sequence a new genome or first try to understand the function of a n...

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