neurodrugdesign.org

CM1103

Structure-based drug design for diagnosis and treatment of neurological diseases. The therapy of neuropsychiatric disorders is limited by the high variability of symptoms and behavioural disturbances. Few drugs are available to address specific subsets of neurological/mental symptoms, and none to aid in diagnosis or to stop the progress of neurodegenerative disorders. Keywords: Structure-based drug design, computational and synthetic chemistry, monoamine receptors, transporters and metabolic enzymes, neu...

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CM1103 | neurodrugdesign.org Reviews

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Structure-based drug design for diagnosis and treatment of neurological diseases. The therapy of neuropsychiatric disorders is limited by the high variability of symptoms and behavioural disturbances. Few drugs are available to address specific subsets of neurological/mental symptoms, and none to aid in diagnosis or to stop the progress of neurodegenerative disorders. Keywords: Structure-based drug design, computational and synthetic chemistry, monoamine receptors, transporters and metabolic enzymes, neu...

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1 publications

2 events

3 objectives

4 working groups

5 members discussion

6 abstract

7 coupons

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CM1103 | neurodrugdesign.org Reviews

https://neurodrugdesign.org

Structure-based drug design for diagnosis and treatment of neurological diseases. The therapy of neuropsychiatric disorders is limited by the high variability of symptoms and behavioural disturbances. Few drugs are available to address specific subsets of neurological/mental symptoms, and none to aid in diagnosis or to stop the progress of neurodegenerative disorders. Keywords: Structure-based drug design, computational and synthetic chemistry, monoamine receptors, transporters and metabolic enzymes, neu...

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neurodrugdesign.org

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CM1103

http://neurodrugdesign.org/publications

Structure-based drug design for diagnosis and treatment of neurological diseases. Gallery – COST Actions. Articles published via action CM1103:. Janez Mavri, Katarina Nikolić, Keith Tipton, Robert Vianello, Kemal Yelekci, Elizabeth Yuriev, Asmund Rinnan, Magdaléna Májeková. Multitarget compounds bearing tacrine- and donepezil-like structural and functional motifs for the potential treatment of Alzheimer’s disease. Vucicevic, J., Nikolic, K., Dobricic, V., and Agbaba, D. ( 2015. Eur J Pharm Sci 68, 94-105.

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CM1103

http://neurodrugdesign.org/members

Structure-based drug design for diagnosis and treatment of neurological diseases. Gallery – COST Actions. This page is for CM1103 members to share content. If you are logged in, you can add new posts through your user dashboard. You are not currently logged in.

3

CM1103

http://neurodrugdesign.org/events

Structure-based drug design for diagnosis and treatment of neurological diseases. Gallery – COST Actions. WG1 (Katarine Nikolic) & WG 2 (Maria Carreiras). Congress Centre of the Slovak Academy of Sciences in Smolenice Castle 50km from Bratislava. Local Organiser: Magdalena Majekova (email: magdalena.majekova@savba.sk) Institute of Experimental Pharmacology & Toxicology Slovak Academy of Sciences Dubravska cesta 9, 84104 Bratislava, Slovakia. WG 3 (Massimo Valoti) & WG 4 (Dorotea Muck-Seler). 8220;Seroton...

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CM1103

http://neurodrugdesign.org/objectives

Structure-based drug design for diagnosis and treatment of neurological diseases. Gallery – COST Actions. Primary Objectives: drug design. To use or develop 3-D structural models for structure-based drug design and computational analysis. To tailor chemical lead compounds to specific multiple targets in the monoamine systems in the brain. To quantify the efficacy of lead compounds to a range of receptors, enzymes and transporters. Secondary Objectives: capacity building.

5

CM1103

http://neurodrugdesign.org/working-groups

Structure-based drug design for diagnosis and treatment of neurological diseases. Gallery – COST Actions. Aims to use or develop 3-D structural models for structure-based drug design and computational analysis. MAVRI, Prof. Janez. NIKOLIC, Dr Katarina. TIPTON, Prof. Keith. Aims to tailor chemical lead compounds to specific multiple targets in the monoamine systems in the brain. BOCA, Prof. Roman. BUTINI, Dr Stefania. CARREIRAS, Dr Maria do Carmo. LINERT, Prof. Wolfgang. MARCO-CONTELLES, Prof. Jose.

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neurodrugdesign.org

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Structure-based drug design for diagnosis and treatment of neurological diseases. The therapy of neuropsychiatric disorders is limited by the high variability of symptoms and behavioural disturbances. Few drugs are available to address specific subsets of neurological/mental symptoms, and none to aid in diagnosis or to stop the progress of neurodegenerative disorders. Keywords: Structure-based drug design, computational and synthetic chemistry, monoamine receptors, transporters and metabolic enzymes, neu...

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