matthewlew.info
About me | Matthew Lew
http://www.matthewlew.info/pages/about.html
I am an Assistant Professor in the Preston M. Green Department of Electrical and Systems Engineering at Washington University in St. Louis. My broad research interest is in the development of optical tools for biology and medicine. During my undergraduate years at Caltech, I worked in the Biophotonics Laboratory. Under Prof. Changhuei Yang creating a lensless camera chip capable of phase imaging and wavefront sensing. For my doctoral research in the Moerner Lab. Matthew D. Lew. Washington University in S...
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Research projects | Matthew Lew
http://www.matthewlew.info/pages/projects.html
Microscope on a chip. Simultaneously measuring the 3D position and orientation of single molecules. We study the complex radiation pattern of single molecules (modeled as electric dipoles), which is often neglected in traditional single molecule-based super-resolution experiments. Ignoring this radiation pattern can produce sizable errors in measurements of single-molecule position, but using a behavior uniquely inherent in the double-lobed nature of the double-helix point spread function, we account...
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Lifelong learning | Matthew Lew
http://www.matthewlew.info/pages/learning.html
Photo by Kris Cheng. There are just too many neat things to see, experience, and read about in the world. This page is dedicated to the notable ideas and skills I've acquired during my lifelong quest for knowledge. Computers and electronics have always captivated my attention, but I've acquired great appreciation for music and cooking too! Piano and string quartet. To cultivate and challenge my creative side, I've decided to take one photo each day of 2014 using the ideas at Project Life 365.
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Research software | Matthew Lew
http://www.matthewlew.info/pages/software.html
Double-Gaussian estimator is calibrated via an axial scan of bright immobile fluorescent emitters (e.g. beads). Template-matching and double-helix recognition algorithm is calibrated via setting an image correlation threshold against single-molecule data. Tiff stacks of SM images are analyzed using template matching followed by double-Gaussian fitting to extract estimates of the molecule positions. 3D localization data can be exported to .csv format for post-processing and visualization.
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Research publications | Matthew Lew
http://www.matthewlew.info/pages/publications.html
Appl Phys. Lett. A von Diezmann, M. Y. Lee, M. D. Lew. And W E. Moerner, “Correcting field-dependent aberrations with nanoscale accuracy in three-dimensional single-molecule localization microscopy,” Optica. 985 (2015). [ OSA news release. PDF - 1.79 MB. S F Lee, M. A. Thompson, H-L. D. Lee, and W. E. Moerner, “Single-molecule photocontrol and nanoscopy,” in Far-Field Optical Nanoscopy. Eds P Tinnefeld, C. Eggeling, and S. W. Hell) 14. 87 (Springer-Verlag, 2015). [ Book chapter. 6407 (2014). [ Journal.
matthewlew.info
Matthew Lew - Assistant Professor, Washington University in St. Louis
http://www.matthewlew.info/index.html
Construction of the Lew Lab in Green Hall at Washington University in St. Louis is complete. Visit our website. For the most current information about our research. I have joined the Department of Electrical and Systems Engineering at Washington University in St. Louis as an Assistant Professor. Postdoc and graduate student positions are available. Interested applicants can contact me via the information below. Read. Matthew D. Lew. Preston M. Green Department of Electrical and Systems Engineering.
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Teaching | Matthew Lew
http://www.matthewlew.info/pages/teaching.html
Teaching is the heart and soul of the university setting; it's what makes the college environment unique and special in contrast to that of the national or corporate laboratory. All too often, there isn't enough incentive and reward for great teaching at universities. However, I enjoy the challenge of explaining abstract concepts in intuitive and concrete ways, and I look forward to contributing to my university's community in future teaching endeavours. Taking Science and Engineering Course Design.
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Community | Matthew Lew
http://www.matthewlew.info/pages/community.html
SUPR 5 Program Committee. Between taking courses and the day-to-day routine in lab, one can easily overlook the people working just across the hall or in the building next door. I've had the pleasure of collaborating with, meeting, and benefitting from the work of extraordinary colleagues during my undergraduate and graduate careers at Caltech and Stanford. Here are some of my attempts to give back to those communities. Stanford Optical Society Co-President. Stanford University Photonics Retreat Chair.