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Regulus Therapeutics Inc. - Investor Relations

Regulus Therapeutics - a leading company developing microRNA therapeutics. Medicines that target the pathways of human disease.

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Regulus Therapeutics Inc. - Investor Relations | ir.regulusrx.com Reviews
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Regulus Therapeutics - a leading company developing microRNA therapeutics. Medicines that target the pathways of human disease.
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Regulus Therapeutics Inc. - Investor Relations | ir.regulusrx.com Reviews

https://ir.regulusrx.com

Regulus Therapeutics - a leading company developing microRNA therapeutics. Medicines that target the pathways of human disease.

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1

Investors - Regulus Therapeutics Inc.

http://ir.regulusrx.com/index.cfm

Annual Reports and Proxies. Keeping our RGLS Family Healthy. Compensation and Financial Rewards. 4:00 PM ET on Nov 8, 2016. Nov 1, 2016. Regulus Reports Third Quarter 2016 Financial Results. Oct 25, 2016. Regulus to Release Third Quarter Financial Results on November 1, 2016. Nov 1, 2016 at 5:00 PM ET. Regulus Therapeutics Inc. Third Quarter 2016 Conference Call. Sep 7, 2016 at 2:55 PM ET. 2016 Wells Fargo Healthcare Conference. RNA therapeutics pipeline complemented by a maturing.

2

RSS News Feeds - Regulus Therapeutics Inc.

http://ir.regulusrx.com/rss.cfm

Annual Reports and Proxies. Keeping our RGLS Family Healthy. Compensation and Financial Rewards. Really Simple Syndication (RSS) is a format designed for sharing web content such as headlines. An RSS feed highlights fresh material for you, so you don't have to repeatedly check a site yourself for updates. How do I use RSS? Some web browsers, such as Firefox. Have RSS readers built in. There are also online aggregators, websites such as My Yahoo. To view a feed in your RSS Aggregator:. Form 4 SEC Filings.

3

Regulus Reports Second Quarter 2015 Financial Results and Recent Highlights (NASDAQ:RGLS)

http://ir.regulusrx.com/releasedetail.cfm?ReleaseID=925688

Aug 4, 2015. File is in Briefcase. Regulus Reports Second Quarter 2015 Financial Results and Recent Highlights. Advanced 'Clinical Map Initiative' with Start of Key Clinical Trials for RG-101 and RG-012-. Maintained Strong Financial Position Ending Q2 2015 with $139.4 Million in Cash-. LA JOLLA, Calif. Aug 4, 2015. June 30, 2015. And provided a summary of recent corporate highlights. The second quarter of 2015 and recent period marked an important time of progression for Regulus," said. Chief Business Of...

4

Events & Presentations - Regulus Therapeutics Inc.

http://ir.regulusrx.com/events.cfm

Annual Reports and Proxies. Keeping our RGLS Family Healthy. Compensation and Financial Rewards. Sep 7, 2016. 2016 Wells Fargo Healthcare Conference. 2016 Wells Fargo Healthcare Conference. Please sign up for Email alerts. Aug 2, 2016. Regulus Therapeutics Inc. Second Quarter 2016 Conference Call. Jun 27, 2016. Regulus Reports Clinical Hold of RG-101. Jun 10, 2016. Jefferies 2016 Healthcare Conference. Jun 7, 2016. Regulus Therapeutics Inc. Conference Call. File is in Briefcase. May 25, 2016. May 12, 2016.

5

Press Releases - Regulus Therapeutics Inc.

http://ir.regulusrx.com/releases.cfm

Annual Reports and Proxies. Keeping our RGLS Family Healthy. Compensation and Financial Rewards. Aug 31, 2016. Regulus to Present at the 2016 Wells Fargo Healthcare Conference. File is in Briefcase. Aug 9, 2016. Regulus to Present at the 2016 Wedbush PacGrow Healthcare Conference. File is in Briefcase. Aug 2, 2016. Regulus Reports Second Quarter 2016 Financial Results. LA JOLLA, Calif., Aug. 2, 2016 /PRNewswire/ - Regulus Therapeutics Inc. (Nasdaq: RGLS), a biopharmaceutical company leading t...LA JOLLA,...

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Biomarkers - Regulus Therapeutics

http://regulusrx.com/regulus-micromarkers

Biology & Pharmacology. Financials & Filings. Events & Presentations. Keeping our RGLS Family Healthy. Compensation and Financial Rewards. RNAs are clinically relevant therapeutic targets and may be ideally suited as biomarkers for numerous disease states. Regulus also believes that. RNA biomarkers are of significant value and may provide opportunities to develop companion diagnostics for its therapeutic candidates and any drugs developed by other companies. For example,. RNAs as biomarkers for MS. R...

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RG-125 - Regulus Therapeutics

http://regulusrx.com/therapeutic-areas/rg-125

Biology & Pharmacology. Financials & Filings. Events & Presentations. Keeping our RGLS Family Healthy. Compensation and Financial Rewards. In April 2015, RG-125 (AZD4076), a GalNAc-conjugated anti-miR targeting. RNA-103/107 ( miR-103/107 ) for the treatment of Non Alcoholic Steatohepatitis ( NASH) in patients with type 2 diabetes/pre-diabetes, was selected as a clinical candidate by AstraZeneca under the companies’ strategic alliance to discover, develop and commercialize. Both NASH and NAFLD are becomin...

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About microRNAs - Regulus Therapeutics

http://regulusrx.com/therapeutic-areas/road-to-the-clinic

Biology & Pharmacology. Financials & Filings. Events & Presentations. Keeping our RGLS Family Healthy. Compensation and Financial Rewards. RNAs are small naturally occurring non-coding RNAs that are 20 to 25 nucleotides in length. In 1993 and since then. RNAs have been identified in almost every species, including humans. They are highly conserved and research has shown that. RNAs function as important regulators of gene expression and play a role in multiple cellular processes. RNAs, 600 of which are co...

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Paul C. Grint, M.D. - Regulus Therapeutics

http://regulusrx.com/leadership

Biology & Pharmacology. Financials & Filings. Events & Presentations. Keeping our RGLS Family Healthy. Compensation and Financial Rewards. Paul C. Grint, M.D. President and Chief Executive Officer. Senior Vice President of Human Capital. Vice President, Finance and Accounting. Victor Knopov, Ph.D. Vice President, Pharmaceutical Development. Michael Huang, M.D. Vice President, Clinical Development. John Grundy, Ph.D. Vice President, DMPK and Toxicology. Christopher Aker, J.D. Vice President, Legal Affairs.

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RG-012 - Regulus Therapeutics

http://regulusrx.com/therapeutic-areas/rg-012-targeting-mir-21-for-alport-syndrome

Biology & Pharmacology. Financials & Filings. Events & Presentations. Keeping our RGLS Family Healthy. Compensation and Financial Rewards. Regulus is developing RG-012, a single stranded, chemically modified oligonucleotide that binds to and inhibits the function of miR-21 for the treatment of Alport syndrome. Alport syndrome is a life threatening genetic kidney disease with no approved therapies. In preclinical studies, RG-012 has demonstrated potent inhibition of miR-21. ATHENA Natural History Study an...

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Publications - Regulus Therapeutics

http://regulusrx.com/publications

Biology & Pharmacology. Financials & Filings. Events & Presentations. Keeping our RGLS Family Healthy. Compensation and Financial Rewards. Shift of microRNA profile upon orthotopic xenografting of glioblastoma spheroid cultures. Halle, B, et al. Convection-enhanced delivery of an anti-miR is well-tolerated, preserves anti-miR stability and causes efficient target de-repression: a proof of concept. Halle B, et al. Jan;126(1):47-55.: 2016-01-01. Androsavich JR, et al. Jan 29;44(2):e13.: 2016-01-29. The Can...

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About microRNAs - Regulus Therapeutics

http://regulusrx.com/about-micrornas

Biology & Pharmacology. Financials & Filings. Events & Presentations. Keeping our RGLS Family Healthy. Compensation and Financial Rewards. RNAs are small naturally occurring non-coding RNAs that are 20 to 25 nucleotides in length. In 1993 and since then. RNAs have been identified in almost every species, including humans. They are highly conserved and research has shown that. RNAs function as important regulators of gene expression and play a role in multiple cellular processes. RNAs, 600 of which are co...

regulusrx.com regulusrx.com

About - Regulus Therapeutics

http://regulusrx.com/about-regulus

Biology & Pharmacology. Financials & Filings. Events & Presentations. Keeping our RGLS Family Healthy. Compensation and Financial Rewards. TOGETHER the Regulus team is leading the way in the discovery and development of. RNA expression is a key factor in many complex multi-factoral diseases, including inflammatory disease, fibrosis, metabolic disease and cancer. RNA therapeutics are oligonucleotides that modulate the function of. Regulus Therapeutics is located in La Jolla, California and is led by a sea...

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Intellectual Property - Regulus Therapeutics

http://regulusrx.com/intellectual-property

Biology & Pharmacology. Financials & Filings. Events & Presentations. Keeping our RGLS Family Healthy. Compensation and Financial Rewards. Regulus has established a robust intellectual property portfolio relating to. RNA drug products and the modulation of. RNA to treat disease. In addition, through its founding companies, Regulus has access to broad and dominant intellectual property estates related to oligonucleotide therapeutics and chemical modifications and delivery technologies useful for. Therapeu...

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RG-101 - Regulus Therapeutics

http://regulusrx.com/therapeutic-areas/rg-101

Biology & Pharmacology. Financials & Filings. Events & Presentations. Keeping our RGLS Family Healthy. Compensation and Financial Rewards. RG-101 has several important properties which may differentiate it from other therapies currently on the market for the treatment of HCV. A novel mechanism of action. Activity against all genotypes. Activity against HCV strains with mutations that cause resistance to oral direct-acting antivirals (DAAs). In a completed Phase I clinical study,. Regulus demonstrated tha...

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