degradome.uniovi.es

Laboratory of Carlos Lopez-Otin

FEBS Jubilee” Award in Biochemistry, the Mexico Award in Science and Technology, and the “Santiago Ramón y Cajal” National Research Award. Together with the development (in collaboration with Chris Overall) of high-throughput methods that tackle these concepts. In parallel studies, the Lopez-Otin group has been involved in the functional annotation of the human genome and other genomes and degradomes of biomedical and evolutionary relevance, from chimpanzees and other primates to mice and whales.

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Laboratory of Carlos Lopez-Otin | degradome.uniovi.es Reviews

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FEBS Jubilee” Award in Biochemistry, the Mexico Award in Science and Technology, and the “Santiago Ramón y Cajal” National Research Award. Together with the development (in collaboration with Chris Overall) of high-throughput methods that tackle these concepts. In parallel studies, the Lopez-Otin group has been involved in the functional annotation of the human genome and other genomes and degradomes of biomedical and evolutionary relevance, from chimpanzees and other primates to mice and whales.

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Laboratory of Carlos Lopez-Otin | degradome.uniovi.es Reviews

https://degradome.uniovi.es

FEBS Jubilee” Award in Biochemistry, the Mexico Award in Science and Technology, and the “Santiago Ramón y Cajal” National Research Award. Together with the development (in collaboration with Chris Overall) of high-throughput methods that tackle these concepts. In parallel studies, the Lopez-Otin group has been involved in the functional annotation of the human genome and other genomes and degradomes of biomedical and evolutionary relevance, from chimpanzees and other primates to mice and whales.

INTERNAL PAGES

degradome.uniovi.es

1

Protease inhibitors

http://degradome.uniovi.es/inhibitors.html

Serine PI Kazal type 1. Serine PI Kazal type 2. Serine PI Kazal type 4. Serine PI Kazal type 4-like 1. Serine PI Kazal type 5. Serine PI Kazal type 5-like 1. Serine PI Kazal type 5-like 2. Serine PI Kazal type 5-like 3. Serine PI Kazal type 5-like 3b. Serine PI Kazal type 5-like 3c. Serine PI Kazal type 5-like 4. Similar to double-headed SPI. Similar to double-headed SPI-like 1. Esophagus cancer-rel. Prot. 2. Acrosin inhibitor precursor-like 1. SPARC related mod. Ca binding 1. HGF activator inhibitor 1.

2

Diseases

http://degradome.uniovi.es/diseases.html

Human hereditary diseases of proteolysis. Reticulate acropigmentation of Kitamura. Inflammatory skin and bowel disease. KO partially resembles disease. Ehlers-Danlos syndrome type VIIC. Dominant hereditary ataxia SCA28. KO exhibits a severe neurodegenerative phenotype. Congenital disorder of glycosylation, type Is. Spinal Muscular Atrophy With Progressive Myoclonic Epilepsy. Osteogenesis imperfecta, type III. Guinea pig model resembles disease. Autosomal recessive intellectual disability (ARID). Mnd2 mou...

3

The Mammalian Degradome Database

http://degradome.uniovi.es/dindex.html

The Mammalian Degradome Database. Proteases are a diverse and important group of enzymes representing 2% of the human, chimpanzee, mouse and rat genomes. This group of enzymes is implicated in numerous physiological processes. The importance of proteases is illustrated by the existence of 126 different hereditary diseases. Due to the importance of proteolytic enzymes in human physiology and pathology, we have recently introduced the concept of. Nat Rev Genet (2003) 4: 544-558. Genome sequence of the brow...

4

Cysteine proteases

http://degradome.uniovi.es/cys.html

Ubiquitin C-terminal hydrolase 1. Ubiquitin C-terminal hydrolase 3. Ubiquitin C-term. hydrolase BAP1. Ubiquitin C-terminal hydrolase 5. Ubiquitin C-terminal hydrolase 4. Sentrin/SUMO protease 5-like 1. Cezanne/OTU domain containing 7B. A20, TNFa-induced protein 3. Ufm-1 specific protease 1. Ufm-1 specific protease 2. Nasal embryonic LHRH factor. Epithelial cell transforming sequence 2 oncogene-like. Hin-1/OTU domain containing 4. OTU domain containing 6B. Ubiquitin specific peptidase like 1.

5

Untitled Document

http://degradome.uniovi.es/jmpf/BioROM2007/contenido/pract/Pr_ESP/index.html

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sindrome-progeria.blogspot.com

progeria: el síndrome de Hutchinson-Gilford: Los genes de Nestór

http://sindrome-progeria.blogspot.com/2013/01/los-genes-de-nestor.html

Progeria: el síndrome de Hutchinson-Gilford. Progeria: el síndrome de Hutchinson-Gilford. Los genes de Nestór. Cuando Néstor se acercó hasta el laboratorio de Carlos López Otín en Oviedo, todo indicaba que el tipo de envejecimiento prematuro que sufría sería del tipo Hutchinson-Gilford, el mismo que el investigador asturiano estaba estudiando tratar dentro de un ensayo internacional. Describen un nuevo tipo de envejecimiento acelerado. En dos pacientes españoles. Los genes de Néstor. Los genes de Nestór.

stemcellsportal.com

What’s the Stem Cell Buzz this Week? – Organoid Update, Cell-based Lasers, and how Aging Impairs Reprogramming | Stem Cells Portal - Stem Cells Journal Online Community

http://www.stemcellsportal.com/what’s-stem-cell-buzz-week-–-organoid-update-cell-based-lasers-and-how-aging-impairs-reprogramming

STEM CELLS Translational Medicine. August 1, 2015. What’s the Stem Cell Buzz this Week? Organoid Update, Cell-based Lasers, and how Aging Impairs Reprogramming. A round up of some the recent stories in the ever-changing world of stem cells/regenerative medicine. Hot Topics - Organoid Update. Has recently published an excellent. Cell-based Lasers to Aid Medical Diagnosis and Treatment? A futuristic new article from. A stem cell with a laser inside? Cell Reprogramming Raising the Age Limit. Cell reprogramm...

ccd.biocuckoo.org

GPS-CCD 1.0 - Computational Predictioin of Calpain Cleavage Sites

http://ccd.biocuckoo.org/links.php

Last update: Feb. 28th, 2014. Computational resources of protein cleavage, etc. :. Last updated: Feb. 26th, 2011. Other resource of calpains and calpain-mediated cleavage. Predict the cleavage of substrates for proteinases including calpains( Verspurten,. A database on calpain, its substrates and calpastatin. A site-specific substrates prediction server was also provided.( duVerle,. Other resource of protein cleavage. Proteases and Protease-mediated cleavage. 2 Predict Putative Substrates of Proteases.

asmb.net

ASMB - American Society for Matrix Biology - Links

http://www.asmb.net/links.php

ASMB is pleased to have a partnership with the following organizations. Please feel free to click on their links to explore these groups further. International Society of Matrix Biology (ISMB). Society for Glycobiology (SFG). American Society for Investigative Pathology (ASIP). North American Vascular Biology Organization (NAVBO). Tissue Engineering International and Regenerative Medicine Society (TERMIS). Cell Adhesion and ECM. Signaling and Cell Biology. Atlases, Tools and More. What is this CD?

es.lynxgenomics.eu

El esfuerzo conjunto de más de treinta científicos - Quiénes somos - Lynx Genomics, desvelando el genoma del lince ibérico

http://es.lynxgenomics.eu/Los_cientificos

El lince ibérico, Lynx pardinus. Genética de la conservación. Mapa de la web. El esfuerzo conjunto de más de treinta científicos. El equipo tras el encuentro en Sevilla. La investigación está financiada por el CSIC y el banco de Santander a través de Proyectos Cero Especies Amenazadas. Una convocatoria de ayudas en la que han competido iniciativas de toda España. Centro Nacional de Análisis Genómico -. Generación de datos, ensamblado y anotación del genoma. El Centro Nacional de Análisis Genómico se creo...

sindrome-progeria.blogspot.com

progeria: el síndrome de Hutchinson-Gilford: 2013-01-20

http://sindrome-progeria.blogspot.com/2013_01_20_archive.html

Progeria: el síndrome de Hutchinson-Gilford. Progeria: el síndrome de Hutchinson-Gilford. Los genes de Nestór. Cuando Néstor se acercó hasta el laboratorio de Carlos López Otín en Oviedo, todo indicaba que el tipo de envejecimiento prematuro que sufría sería del tipo Hutchinson-Gilford, el mismo que el investigador asturiano estaba estudiando tratar dentro de un ensayo internacional. Describen un nuevo tipo de envejecimiento acelerado. En dos pacientes españoles. Los genes de Néstor. Los genes de Nestór.

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degradolaw.com

Bergen County Attorneys | Law Firm in Hackensack NJ

540 Hudson Street, 5th Floor Hackensack, NJ. Skill Dedication. Results. Schedule a Free Consultation. Child Support and Custody. Patient Health Insurance Denial. About DeGrado Halkovich LLC. Paul K. DeGrado. Jeffrey M. Halkovich. Howard I. Gordon. Christopher S. Mahoney. Your Trusted Law Firm in Bergen County, NJ. Aggressively Handling Legal Matters With a Client Centered Approach. Skill Dedication. Results. On behalf of our clients' and have helped thousands of our clients' achieve their desired result&...

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Degrado Marconi

Mercoledì 8 maggio 2013. Einstein and Keplero di nuovo pulite. Rimossi anche i manifesti abusivi e denunciato il cartellone irregolare. Quasi un anno fa denunciavamo il degrado delle scuole Einstein e Keplero:. Http:/ degradomarconi.blogspot.it/2012/05/il-degrado-si-vede-dalle-scuole.html. Il 27 febbraio scorso non era cambiato niente, la situazione era identica. Il 7 marzo ci hanno risposto i PICS, comunicandoci l'avvenuta pulizia dei muri perimetrali delle scuole. Aspettiamo una risposta dalla Polizia ...

degradome.net

Main Page - Degradome.net

Retrieved from " http:/ Degradome.net/index.php/Main Page. Related Links [ Edit. This page was last modified on 25 October 2015, at 05:31. This page has been accessed 23,941 times. Content is available under BioLicense: the freest license.

degradome.org

Main Page - Degradome.org

Getting your own Genome. Possible genomic diseases of you. Storing your genome in you PC. Viewing your genetics family. A brief guide to genomics from NHGRI. Interesting things in your Genome. Compare your genome with other people's. The principle of universal genome. Fully sequenced human genomes. Fully sequenced female human genome. Human Y chromosome genomics. Genomics Major Paper Publication. Your writing contribution to Genomics. Daphnia Genomics Consortium (DGC). Rice Genome at BGI China. By Nation...

degradome.uniovi.es

Laboratory of Carlos Lopez-Otin

FEBS Jubilee” Award in Biochemistry, the Mexico Award in Science and Technology, and the “Santiago Ramón y Cajal” National Research Award. Together with the development (in collaboration with Chris Overall) of high-throughput methods that tackle these concepts. In parallel studies, the Lopez-Otin group has been involved in the functional annotation of the human genome and other genomes and degradomes of biomedical and evolutionary relevance, from chimpanzees and other primates to mice and whales.

degradomics.net

Main Page - Degradomics

MediaWiki has been successfully installed. Consult the User's Guide. For information on using the wiki software. MediaWiki release mailing list. Retrieved from " http:/ Degradomics.net/index.php/Main Page. Related Links [ Edit. This page was last modified on 17 August 2006, at 02:59. This page has been accessed 18,688 times. Content is available under BioLicense: the freest license.

degradomics.org

Main Page - Degradomics

MediaWiki has been successfully installed. Consult the User's Guide. For information on using the wiki software. MediaWiki release mailing list. Retrieved from " http:/ Degradomics.org/index.php/Main Page. Related Links [ Edit. This page was last modified on 17 August 2006, at 02:59. This page has been accessed 14,219 times. Content is available under BioLicense: the freest license.

degradon.com

degradon.com - Registered at Namecheap.com

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degradon.net

degradon.net - Registered at Namecheap.com

This domain is registered at Namecheap. This domain was recently registered at Namecheap. Please check back later! This domain is registered at Namecheap. This domain was recently registered at Namecheap. Please check back later! The Sponsored Listings displayed above are served automatically by a third party. Neither Parkingcrew nor the domain owner maintain any relationship with the advertisers.

degradopublishing.com

Comfort and Healing

A book of inspiration and help for those who are grieving. Poignantly crafted poetry, written by one who has lived the grief experience, lifts one from depths of despair to heights of hope and discovery. Expressive photography launches visual escape to beauty and spiritual impact. Bible verses give the grieving person. An interactive journal, revealing emotions from the author’s own pages give space for the reader to express her/his feelings, making. For healing, hope and a. The authors may be reached at.