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Bernal-Mizrachi Laboratory

Our Lab studies the molecular mechanism by which NF-kB produces lymphomagenesis, focusing on protein interactions and the identification of NF-kB depedent genes that contribute to pathologic lymphoid formation. Constitutive activation of NF-kB has been implicated in tumorigenesis of several lymphoid malignancies such as Non-hodgkins, Hodgkin Lymphoma, and multiple myeloma. For this reason the NFkB pathway is an attractive therapeutic target to be explored.

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Bernal-Mizrachi Laboratory | bernal-mizrachilab.com Reviews
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Our Lab studies the molecular mechanism by which NF-kB produces lymphomagenesis, focusing on protein interactions and the identification of NF-kB depedent genes that contribute to pathologic lymphoid formation. Constitutive activation of NF-kB has been implicated in tumorigenesis of several lymphoid malignancies such as Non-hodgkins, Hodgkin Lymphoma, and multiple myeloma. For this reason the NFkB pathway is an attractive therapeutic target to be explored.
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1 research
2 lab members
3 contributions
4 lab resources
5 constructs
6 publications
7 science links
8 photo gallery
9 bernal mizrachi labolatory
10 all righst reserved
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Bernal-Mizrachi Laboratory | bernal-mizrachilab.com Reviews

https://bernal-mizrachilab.com

Our Lab studies the molecular mechanism by which NF-kB produces lymphomagenesis, focusing on protein interactions and the identification of NF-kB depedent genes that contribute to pathologic lymphoid formation. Constitutive activation of NF-kB has been implicated in tumorigenesis of several lymphoid malignancies such as Non-hodgkins, Hodgkin Lymphoma, and multiple myeloma. For this reason the NFkB pathway is an attractive therapeutic target to be explored.

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1

Bernal-Mizrachi Laboratory

http://www.bernal-mizrachilab.com/labmembers.html

Leon Bernal-Mizrachi, MD. Assistant Professor, Hematology/Medical Oncology. Emory University School of Medicine. 1365 Clifton Rd NE, C-3005. Atlanta, GA 30322. Email: xiangxue guo@yahoo.com. Taryel L. Randolph. Winship Cancer Institute of Emory University. Dept Hematology and Medical Oncology. 1365C Clifton Road, Suite 1152. Atlanta, GA 30322.

2

Bernal-Mizrachi Laboratory

http://www.bernal-mizrachilab.com/contributions.html

Each year, approximately 7.6 million people living worldwide die from cancer, it is the number one killer in America, according to the American Cancer Society. The mission of Bernal Mizrachi Laboratory is research and study the immune system cancers such as Lymphomas and Myelomas. Our studies have provided new genetic indicators that could guide doctors to select the best combination of therapies. Our commitment is to improve the outcome and reduce the toxicity of the therapies used to treat Lymphoma...

3

Bernal-Mizrachi Laboratory

http://www.bernal-mizrachilab.com/index.html

Our Lab studies the molecular mechanism by which NF-kB produces lymphomagenesis, focusing on protein interactions and the identification of NF-kB depedent genes that contribute to pathologic lymphoid formation. Constitutive activation of NF-kB has been implicated in tumorigenesis of several lymphoid malignancies such as Non-hodgkins, Hodgkin Lymphoma, and multiple myeloma. For this reason the NFkB pathway is an attractive therapeutic target to be explored.

4

Bernal-Mizrachi Laboratory

http://www.bernal-mizrachilab.com/labresources.html

Lab Resources - Please contact us for further information: lbernal@emory.edu. Diffuse large cell lymphoma cell lines, (DLCL, ABC type) : OCI-LY3 and OCI-LY10. Diffuse large cell lymphoma cell lines, (DLCL, GC type): SUDHL-4 and SUDHL-6. EBV DLCL : Daudi and Raji. HHV8 lymphoma cell lines: BCBL, BC1 and BC2. HTLV1 adult T-cell lymphoma cell lines: MT2, MT4, SC (derived from Tax-transgenic mice). Multiple myeloma cell lines: OPM and RPMI. High Through Put Data Analysis.

5

Bernal-Mizrachi Laboratory

http://www.bernal-mizrachilab.com/sciencelinks.html

American Association for Cancer Research.

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Bernal-Mizrachi Laboratory

Our Lab studies the molecular mechanism by which NF-kB produces lymphomagenesis, focusing on protein interactions and the identification of NF-kB depedent genes that contribute to pathologic lymphoid formation. Constitutive activation of NF-kB has been implicated in tumorigenesis of several lymphoid malignancies such as Non-hodgkins, Hodgkin Lymphoma, and multiple myeloma. For this reason the NFkB pathway is an attractive therapeutic target to be explored.

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